A Comparative Study between C-Reactive Protein and Procalcitonin in Iraqi Burn Patients

Abstract

Association between Procalcitonin (PCT) and C-reactive protein (CRP) and burn injury wasevaluated in 80 burned patients from Al-Kindy and Imam Ali hospitals in Baghdad-Iraq. Patientswere divided into two groups, survivor group 56 (70%) and non-survivor group 24 (30%). PCTwas estimated using (Human Procalcitonin ELISA kit) provided by RayBio/USA while CRP wasperformed using a latex agglutination kit from Chromatest (Spain).Our results declared that the mean of Total Body Surface Area (TBSA %) affected were 63.5%range (36%–95%) in non-survivor patients, while 26.5% range (10%–70%) in survivor patients.There is a significant difference between the two groups (P = 0.00), the higher mean percentageof TBSA has a significant association with mortality.Serum PCT and CRP were measured at the three times of sampling (within the first 48hrfollowing admission, after 5thdays and after 10th days). The mean of PCT serum concentrations innon-survivor group (2638 ± 3013pg/ml) were higher than that of survivor group (588 ±364pg/ml). Significantly high levels of CRP were found between the survivor and non-survivorgroups especially in the 10th day of admission P=0.000, present study show that significantdifferences is found within the non-survivor group through the three times P= 0.01, while resultswere near to significant differences within survivor group through the three times (P= 0.05).