Synthesis of some New Schiff Bases Containing Acridone Moiety

Abstract

The 2-[(4'-amino-3,3'-dimethylbiphenyl-4-yl)amino]benzoic acid (II) was synthesized by Ullmann-Goldberg coupling by reaction of 3,3'-dimethylbiphenyl-4,4'-diamine (I) with 2-chlorobenzoic acid. The compound (II) was cyclized by poly phosphoric acid (PPA) to give 2-[(4-amino-3-methyl)phenyl]-4-methylacridin-9 (10H)-one (III). New Schiff bases (IVa-j) and (Va-d) has been prepared by reaction of compound (III) with aromatic aldehydes and cyclic ketones respectively