Evaluation of the Analgesic Effect of Four Intra-Articular Ozone Injections in Knee Osteoarthritis

Iyad Abbas Salman

Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية
ISSN: 16088360 Year: 2016 Volume: 15 Issue: 2 Pages: 211-214
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية


ABSTRACT:BACKGROUND: Knee osteoarthritis (OA) is a degenerative disease of the knee joint. There is no cure for the disease, but some treatments attempt to slow disease progress.Intraarticular ozone injection is increasingly being applied. In knee osteoarthritis it represents a complementary treatment method which provides pain relief, decongestion, subsidence of bruises (hematomas), a reduction in temperature and an improvement in motility.OBJECTIVE: To evaluate the analgesic effect of 4 subsequent intra-articular ozone-oxygen injections in knee joint osteoarthritis. PATIENTS AND METHODS:It was a prospective, randomized clinical study, done on 30 knee joints, all patient were with history of OA of knee joint & suffering from long standing pain & they have long history of medical therapy. After taking patient consent, 5 weekly sessions of intra-articular 5 ml (25 μg/ml ) ozone injections were done under complete aseptic technique. Numerical Analog Pain score has been assessed and recorded before each session.RESULTS: It was found that there was highly significant difference between each 2 subsequent sessions and the p-value was below 0.01 in all times.CONCLUSION: Subsequent Intra-articular ozone injection had significant analgesic effect in knee joint osteoarthritis


KEY WORDS: intraarticular ozone --- knee joint osteoarthritis --- chronic pain.