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Synthesis and identification of Five Membered Rings Heterocyclic Compounds Derived from Trimethoprim

Ali M. Attia --- Ebtihal K. Abdallah --- Hala M. G. Alzahawy --- Olfat A. Nief

Al-Nahrain Journal of Science مجلة النهرين للعلوم
ISSN: (print)26635453,(online)26635461 Year: 2018 Volume: 00 Issue: 1 Pages: 1-7
Publisher: Al-Nahrain University جامعة النهرين

Abstract

This study includes the preparation and identification of five membered rings Hetrocyclic Compounds derived from Trimethoprim by reaction Schiffs, bases(1a-h)(prepared by reaction some aromatic aldehyde with Trimethoprim using Microwave technique) with Hydroxy acidic acid (Glycolic acid), the prepared compounds were identified by I.R spectroscopy and some of them by NMR spectroscopy and C.H.N.S micro analysis.

Keywords

Synthesis Four Membered Rings --- Heterocyclic --- Trimethoprim.