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Synthesis of some Quinazolin One Derivatives for Their Antimicrobial Activity

Hadel A. Abdalgane --- Hammed H. Mohammed --- Firyal Weli Askar

Al-Nahrain Journal of Science مجلة النهرين للعلوم
ISSN: (print)26635453,(online)26635461 Year: 2018 Volume: 00 Issue: 1 Pages: 17-25
Publisher: Al-Nahrain University جامعة النهرين

Abstract

A series of derivatives for compound 2-(4-chlorophenyl)-4H-benzo[d] [1,3] oxazin-4-one with different aromatic substitution were proved. The newly synthesized derivatives have been supported by spectral data FTIR and H1 NMR. All the synthesized compounds were screened for their antimicrobial activity and compared with drug Amoxicillin as reference.

Keywords

Quinazolinone --- Antimicrobial activity --- 2-Azetidinone --- 4-thiazolidinone.