Abstract

Irritable bowel syndrome (IBS) is one of the commonest disorder of the gastrointestinal tract, IBS is long standing dysfunction associated with abdominal pain for which no organic cause can be found . a fifty three patients were included in this study all of them diagnosed as irritable bowel syndrome clinically after excluding organic causes. The patients receive a treatment with " librax " (chlordiazepoxide 5 mg & clidinium 2.5 mg ) before meal twice daily plus " spasmopan"( hyoscine N- butylbromide 10 mg ) after meal three times daily . The treatment continue for 1.5 -2 month .The results showed an improvement in 68% of the patients . No significant differences observe except in female , age group of 20-30 years old , patients with positive family history of the disease & patients with psychotic disorders (stress , worried & anxiety ). Initiation of combine drugs therapy plus psychotherapy a good approach in treatment of irritable bowel syndrome

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