THE EFFECT OF glycyrrhiza glabra AND DIOSPYROS KAKI FRUITS IN INHIBITING THE CHROMOSOMAL ABERRATIONS RESULTED FROM SODIUM SULFATE TREATMENT IN HUMAN LYMPHOCYTE

Abstract

To study the role of Glycyrrhiza glabra and Diospyros kaki fruits extracts, active compounds were detected. The first extract contained glycoside, tannines, alkaloids, saponines, terpines, steroides, flavones and coumarins, while the second extract contained phenolics and resins in addition to the compounds mentioned above with an exception of alkaloids and coumarins. The inhibition effect of the extracts on the chromosomal aberration resulted from sodium sulfate as mutagenic agent in human lymphocyte cells (In vitro) was evaluated at concentrations of 10, 15, 25, 50, 100 mcg/ml. Results showed increasing in inhibition of the extracts on chromosomal aberration with the increase of the concentrations used and its interaction.