Conductivity and Spectrophotometric Study of Drugs and their Complexes with Some Metal ions in Aqueous Solution

Abstract

This research is used to study of some antibiotics (Cephelaxine ,Amoxicillin, and Chloramphenicol) by Conductivity & U.V. in aqueous solution at pH 7 at a wide range of concentration and also to study their complexes with some metal ions (Fe , Cu , Ca). The complexes were identified and studied using the techniques of electrical conductivity and spectrophotometric (U.V.) methods to determine their behaviour at (37 oC) and at pH 7 . The equivalent conductivity at infinite dilution (Λo), the ion association constant (KA) and the main distance between ions (R) at the best fit values of standard deviation (σΛ) are calculated for each antibiotic and also the conductivity parameters for the complexes. This method is then compared with the spectrophotometric method by studying the complexes by measuring the absorbance in the (U.V.) region