Nucleophilic Substitution Reactions of Methyl Malonyl Chloride with Some Nucleophilic Reagents

Abstract

New method for synthesis of new methyl malonamic acid derivatives have been employed successfully via the nucleophilic substitution reactions of methyl malonyl chloride with urethane followed by the reaction with some of nucleophilic reagents (amine, alcohol and water) in the same medium and reaction vessel. The structural formulas of the synthesized compounds were elucidated by physical and spectroscopic methods.