The Relegation of Female Hormones Level with Blood Lipids Concentration in Breast Tumors

Abstract

In this study the Biochemical and hormonal changes has been demonstrated on the serum of (68) females, with Benign and Malignant Breast cancer, and (15) controls, whose ages range was (18-67) years. Samples had been obtained from Hazim Al-Hafed hospital for tumors and Al-Zahrawi Hospital (Breast Disease Center). The study included measurement of the concentration of cholesterol, triglycerides, High Density Lipoproteins (HDL), Low Density Lipoproteins (HDL) and Very Low Density Lipoproteins (VLDL), as well as Luteinizing Hormone (LH) and Follicle – Stimulating Hormone (FSH). The results showed significant increase (p<0.01) in cholesterol, triglycerides and (VLDL) concentration, while there is no diflerence in serum (HDL) and (LDL) concentrations comparing with controls. The results also showed significant increasment (p<0.001) in (FSH) level in all females with breast cancer while there was significant increament (p<0.05) in (LH) level in follicular period and significant decrease (p<0.05) in postmenopausal.The results showed no change in all parameters in serum of females with benign tumors comparing with controls.