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Immunology of E. coli Persistant pyuria

Ibrahim M.S. Shnawa --- Baha H.H. Al Amidi

Medical Journal of Babylon مجلة بابل الطبية
ISSN: 1812156X 23126760 Year: 2004 Volume: 1 Issue: 3-4 Pages: 300-307
Publisher: Babylon University جامعة بابل

Abstract

Fourty Persistent Pyuria Patients were diagnosed as E. coli persistant pyuria . Of which 33 were Immune (In a sense of mounting normal adapted immune response) and seven were immunocompromised (In a sense of mounting subnormal adapted immune response .The female / Male ratio was 13/27 . The patients age range was 30-70 years .The median total serum protein was 7.274 g/dl . Likewise the median serum total globulin was 4.302 g/dl . while the median of systemic to the median of mucosal globulin ratio was 0.69 . These scores were generally higher than those of normal control subjects . The median immunoglobulin class concentrations were 2.339, 0.195 and 0.309 g/dl to classes IgG , IgM and IgA respectively . E. coli immunodominant epitopes were intiating specific circulating and mucosal agglutinin as well as significant leucocytes inhibition factors in immune patients and nonsignificant in immunocompromized . Thus, E. coli epitopes could be of T dependent type and activate either or both Th1 and Th2 lymphocyte, or it might be of T independent epitope type