Seasonal measurement of serum total cholesterol and malondialdehyde in healthy subjects

Abstract

Objective: To evaluate serum total cholesterol (TC) and malondialdehyde (MDA) inhealthy subjects in winter and summer seasons.Subjects and methods: This study was conducted at the college of Pharmacy,University of Mosul. Twenty healthy subjects, non-smokers, free from anymedication were included in this study. Five mL of blood sample from each subjectwas taken in winter and other blood sample was taken from the same subject insummer and analysed for serum TC and MDA.Results: No significant difference was noticed between winter and summer for serumTC (٤.٦٥±٠.٥٩ mmol/L versus ٤.٤٥±٠.٦ mmol/L). However, serum MDA insummer (١.١٩±٠.٢ µmole/L) was significantly higher (P < ٠.٠١) than in winter(٠.٩٦±٠.١٦ µmol/L)Conclusion: Oxidative stress increases in hot weather. Seasonal serum lipid profilelevels depend on life style of the people and their geographical location.