The Antagonistic role of Cinnamon on a destructive effect 0f Alloxan on the rat testis . A Histological Study

Abstract

ABSTRACT: BACKGROUND: Diabetes mellitus is a chronic metabolic disorder characterized by a high blood glucose concentration (hyperglycemia ) which is due to insulin deficiency and / or insulin resistance . As a consequence of the metabolic derangements various complications develop , so the aim of this investigation is to study(histological ) the role of cinnamon – oil on the testis tissue of alloxan – induced diabetes rat . METHODS AND METHODS : Forty -six male rats were used and divided into 3 groups : group I , 6 = animal control . group II , 20 = treated with alloxan and the 3 rd group , 20 = treated with alloxan + cinnamon . RESULTS : Testis of group I revealed normal distribution of seminiferous tubules and spermatozoa filled the lumen of these tubules . Group II showed reduction in number of seminiferous tubules , and absence of spermatozoa in their lumen , besides the significant decrease in testis weight . Group III elicited retrained these changes to approximately its normal view . CONCLUSION : This herbs ( cinnamon ) decrease or protect the destructive effect of alloxan on testis tissue