Comparative Study for the Hypoglycemic Effect of (Trigonella foenum-graecum )Seed, ( Syzygium aromaticum ) Fruit Extracts and Insulin in Alloxan-Induced Diabetic Female Albino Mice .

Abstract

The present study has been carried out to determine the hypoglycemic effect of (Trigonella foenum-graecum) seed and (Syzygium aromaticum) fruit extracts administration as well as insulin injection in alloxan – induced diabetic female albino mice. Forty mice were randomaly assigned into two groups, control (10 mice) drenched with drinking water, while treated group (30 mice) were injected with alloxan (150 mg / kg) body weight. Treated group was further divided into three equal groups , first group drenched with (Trigonella foenum-graecum ) seed extracted (200 mg / kg .b .w ) , second group drenched with (Syzygium aromaticum ) fruit extracted ( 200 mg / kg .b .w ) , and third group injected with insulin ( 0.02 unit / mg / kg . b. w ) . The results revealed potent hypoglycemic effect of both (Trigonella foenum-graecum) seed extract and (Syzygium aromaticum) fruit extract in diabetic groups which showed no significant differences when compared with that of control and Significant differences when compared with that of alloxan group . On the other hand (Trigonella foenum-graecum) seed extract revealed more potency than (Syzygium aromaticum) fruit extract.