Effect of (curcume longa )on liver enzymes and the function of the kidney.

Abstract

This study was design to find out the effect of curcume on the liver enzymes and the function of the kidney by giving these animals curcume 150,300mg/kg/body weight with water in adult female rats .Twenty one adult female rats was divided randomly into 3groups :control group which was given normal drinking water and diet ,treatment (k1)which wasgiven curcume150mg/kg/body weight with drinking water ,treatment(k2)which was given curcume 300mg/kg/body weight for five weeks .Blood samples were taken in 1,3,5weeks of the expermental period to measure (urea,creatinine,Gpt,Got,alkaline phosphatase ,total serum bilirubin).the study revealed the treatment by curcume150mg/kg ,300mg/kg due to increase in the liver enzymes and metabolic product of the kidneythe conclution from this study curcum play role in the function of the liver enzymes and lead to increase the production of secretion of bile salt and this lead to filteration the blood from the product and toxic material.