Endoscopic Fndings in Uraemic Patients With Dyspeptic Symptoms

Abstract

Objective:1-To correlate the endoscopic findings with clinical diagnosis of patients with chronic renal failurein regard to the cause of their dyspeptic symptoms.2-to find out the frequency of various mucosal lesions of upper gastrointestinal tract in these patients as shown by endoscopic examination in comparism to the findings in non renal failure duspeptic patients.Patients and methods:Aprospective study carried out between March 2007 to september2007 on the admitted 25 uraemic patients with dyspeptic symptoms in AL-Sader teaching hospital and AL-Hakeem general hospital in AL-NAJAF city in IRAQ.(19 peritoneal dialysis and 6 patients on conservative treatment).History and clinical examination had done for each patients and clinical diagnosis of the dyspeptic symptoms was made before the endoscopic examination.Blood urea was measured in all patients and the patients are classified arbitrary in to four groups according to the level of the blood urea before endoscopic examination. Also the endoscopic results of 1000 dyspeptic non uraemic patients examined during the same period were also analyzed and compared with those of uraemic patients. Results:Clinical diagnosis depending on history and clinical examination was as follows. 4 patients highly suggestive of esophagitis ,9 patients highly suggestive of gastritis,12 patients highly suggestive of peptic ulceration. While the endoscopic results of the of the dyspeptic uraemic patients were 15 patients got dudenitis,12 patients got gastritis,7 patients got esophagitis,3 patients got esophageal hiatus hernia,3 patients with normal finding. Regarding the endoscopic the endoscopic findings of 1000 cases of non uraemic patients with dyspeptic symptoms were esophagitis in 115 of the cases,gastritis in 113 of the cases,gastric ulcer in 35 of the cases,dudenitis in 190 of the cases,dudenal ulcer in 313 of the cases,other normal findings and others in 277 of the cases.Conclusion:This study is clearly shown no peptic ulcer was detected in uraemic patients involved in our study, while there is increase in the frequency of mucosal lesions in the form of esophagitis, gastritis, and dudenitis in comparism with non uraemic patients with dyspeptic symptoms.