Lipid Peroxidation in Oral Cancer

Ghaydaa H. Badri

Basrah Journal of Surgery مجلة البصرة الجراحية
ISSN: 16833589 / ONLINE 2409501X Year: 2003 Volume: 9 Issue: 1 Pages: 98-100
Publisher: Basrah University جامعة البصرة


In this study, 20 patients with oral cancer (confirmed by histopathological examination) and 21 control subjects were included, to evaluate the degree of lipid peroxidation (LP) in oral cancer. Serum malondialdehyde (MDA) was significantly higher among oral cancer patients (5.842.19 nMol/L) compared to control subjects (1.790.61 nMol/L), (P<0.001). We conclude that oral cancer is accompanied with a significant degree of free radicals formation resulting in increased LP. Therefore, serum MDA level may serve as a marker for oral cancer.