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HISTOLOGICAL STUDY ON THE STRUCTURAL CHANGES OF PLACENTA IN SMOKING IRAQI MOTHERS

KHALIDA K JBARA

Basrah Journal of Surgery مجلة البصرة الجراحية
ISSN: 16833589 Year: 2008 Volume: 14 Issue: 2 Pages: 18
Publisher: Basrah University جامعة البصرة

Abstract

The placenta was chosen as a possible sample for detection of degenerative changes bytobacco smoking in the human pregnant female. Passive smoking mother during pregnancy isassociated with increase of collagen content of the villi, decrease fetal weight, increase in thenumber of villi, increase of trophoblastic apoptosis and increase in the thickness of maternofetalbarrier. Sections, 3-5 micron thickness of 40 full term placentae of passive smoking mothersand 30 number of gestational matched placenta were used as control, they were studiedunder light microscope. Appreciable degenerative changes were found in the group of passivesmoker females, he main findings were: thickening of the basement membrane of placentalvillus, increase in the collagen content of the villus, and increase in the syncytial budding,increase in the materno-fetal barrier thickness and extensive loss of trophoblast. This studyconcluded that tobacco is harmful to the human tissue and vascular system in generalsuggesting that smoking results in deteriorating organ structure and function.�