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18-ACUTE ERYTHRO-LEUKEMIA (DI GUGLIELMO SYNDROME) IN A YOUNG ADULT IN BASRAH CITY

Thya Al-Saadiat --- Zuhair Al-Barazanchi.

Basrah Journal of Surgery مجلة البصرة الجراحية
ISSN: 16833589 Year: 2009 Volume: 15 Issue: 2 Pages: 100-103
Publisher: Basrah University جامعة البصرة

Abstract

Introduction Giovanni Di Guglielmo first described erythroleukemia, a leukemia composed of purely erythrocytic precursors in 1926, and the disorder is often still referred to as acute Di Guglielmo syndrome. It is classifiedas an M6 subtype of acute myelogenous leukemia (AML) in the French-American-British (FAB) classification system based on morphologic andcytochemical criteria1a. Acute erythroleukemia accounts for 3-5% ofall de novo AMLs and 20-30% of secondary leukemias. It is very rare inchildren. The incidence of erythroleukemia increases in peopleolder than 50 years2 Mazzella et al (2000) described 2 peaks, one in theseventh decade of life and a second, smaller peak in the fourth decade of life.

Keywords

LEUKEMIA --- GUGLIELMOH Saeed