clinical and histological evaluation of the effect of bovine saliva on the experimentally induced open wounds on rabbit

Abstract

The use of bovine saliva as a wound dressing rriaterial. In the present study, bovine saliva was_applied to experimental by second intention on the eilrperimental wounds in rats , and it's effects on_ epithelization, wound contraction newly formed granulation tissue. T f I. We evaluated the time interval required for wound healing using a standard wound with andwithout bovine saliva. The bovine saliva did interfere with a normal development of wound healing. -Histological evaluation was considered to parameters the effect of bovine saliva on woundhealing. The effect appear to be due to an increase collagen activity , consequently improving the T_ collagen matrix and enhancing the breaking strength by lysosomes with saliva