Effect of Dialysis Duration on the Immunochemical Changes

Abstract

Objective: To study the effect of dialysis on the immunochemical changes of some interleukins and other biochemical parameters.Design setting: A total of 25 patients with end stage renal disease (mal and female) underwent dialysis with different duration were included in this study. Their age ranged from (22-75).The patients were divided according to the duration, the first group who received dialysis less than one year and the second group who received dialysis more than one year Healthy control group were sex, ethnic, matched and semimatched in age with patients group were selected. Results: Using ELISA technique, serum IL-1α and IL-8 were estimated for dialyzed patients when divided in to two groups (less than one year and more than one year). Also Serum FT3 and albumin were also measured for the above two groups compared with healthy controls. All the above parameters showed different pattern. Conclusion: Hemodialysis duration was influenced serum levels of interleukins and other biochemical parameters.Key words: End stage renal disease, Dialysis, Interleukins.