Synthesis ,Characterization and antibacterial activity study of Cu(II) and Co(II) complexes with Nystatin

Abstract

Cu(II) and Co(II) complexes were prepared by the reaction of metal ions with Nystatin in (1:1) and (1:2) metal ratio, respectively. These complexes were characterized by IR ,UV-Vis spectroscopy and conductivity measurements.All complexes shows relatively high antibacterial activity against S.aureus and E.coli whereas Nystatin has no antibacterial activity against the same bacteria. All complexes are weak electrolytes in DMSO solution .