Histopathological Study of Liver Tissue in Infected Sheep with

Abstract

The present study deals with histopathologcally of sheep liver infected withhydatid cysts caused by from Echinococcus granulosus The pieces of liver werefixed soon after they taken out from the animal’s body and sections prepared andstained with haematoxylin and eosin,(HE), then were examined microscopically.The cysts were differ in size and intensity of histopathological changes proportionalinversely with the size of cyst. The pathological changes appeared clearly in regionsclose to the cyst wall and the microscopic examination showed that the hepatocyteswere deformed in size and shape due to reduced cytoplasmic contents and manygaps were seen around the fibrous cyst wall,also showed nuclear pykonosis andelongated cells in some area of tissue.These effects were seen at the distance fromthe cysts wall. also there were some fibrotic tissue near the cyst wall with someareas of calcifications.The present study indicated that the hydatid cyst fluid produced high toxic effect intissue surrounding the cysts caused by both histopathologically and mechanicallychanges.