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Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients

Wala'a E. Jasim --- Batool A. Al-Haidary --- Yacoob Y. Al-Rubayei

Journal of the Faculty of Medicine مجلة كلية الطب
ISSN: 00419419 Year: 2007 Volume: 49 Issue: 1 Pages: 116-120
Publisher: Baghdad University جامعة بغداد

Abstract

Background: Asthma is an allergic hypersensitivity disease in which many mediators play a role in its pathogenecity. One of these etiological agents is the mediators such as Interleukin-5 (IL-5). The aim of this study to demonstrate the association between IL-5 and obesity in asthma development. Materials & Methods: One hundred and four sera samples for asthma cases have been studied in comparison with 41 non-asthmatic bronchitis as a patient controls beside 30 apparently healthy controls. Cytokine has been estimated using ELISA method in correlation with Body Mass Index (BMI). Results: This study revealed a significant correlation between IL-5 concentration and BMI (P<0.05), particularly among females. Conclusion: There is certain correlation between obesity and asthma accompanied by IL-5. Key

Keywords

Asthma --- IL-5 --- ELISA --- BMI.