Synthesis and Preliminary Antibacterial Study of New 2-Mercapto-1, 3- Benzothiazole DerivativesWith Expected Biological Activity

Abstract

Abstract:Benzothiazoles are bicyclic ring system which have multiple applications. as antitumor ,antiviral , antibacterial , anthelmintic and some of them showed glucose level.20 lowering effect.Accordingly, research is conducted to synthesize and evaluate some new derivatives asantibacterial agents by linking 2-aminobenzothiazoles with glycine and glycine derivatives.S-benzo[d]thiazol-2-yl2-(2-(2,4-dinitrophenyl)hydrazinyl) ethanethioate has been testedon hospital strains of E.coli and pseudomonas and found to have good activity at differentconcentrations.