دراسة مستويات عامل النمو المشابه لهرمون الانسولين -1 (IGF-I) وعلاقته مع بعض المعايير في مرضى داء السكري غير المعتمد على الانسولين

Abstract

This study was performed to assessment the Insulin-like growth factor – I levels in the non insulin dependent diabetic patient and its relationship with other parameters like (body mass index, fasting blood glucose, Glycocylated hemoglobin HbA1c and microalbuminuria ) . In the type II diabetic patients, the results have showen Low significant (p<0. 05) in the levels of IGF-I in the patients compared with control groups. And there was significant elevations (p<0.05) in the levels of fasting blood glucose, glycated hemoglobin and microalbuminuria compared with contral groups. Body mass index appear no significant differences (p<0.05) . The assessment of relationship between parameters have shown significant correlation between levels of IGF-I and glycated hemoglobin HbA1c in male and female and also between IGF-I levels and duration in female and microalbuminuria in male, no significant in female between IGF-I levels and microalbuminuria. And no significant between IGF-I and F.B.G. in female and male , Duration of diabetes in male.we conclude that decline in the levels of IGF-I dependent on duration of diabetes in non insuline dependent diabetic patients found different correlations among B.M.I. , F.B.G. , HBA1C and microalbuminuria .