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The effect of zinc and selenium on blood pictures and concentration of some hormones in albino male rats exposed to oxidative stress.

تأثير عنصري الزنك والسيلينيوم في صور الدم وتراكيز بعض الهورمونات في ذكور الجرذان البيض المعرضة للاجهاد التأكسدي ببيروكسيد الهيدروجين

SuhaHussin Mohammed AL-Mashhadany سهى حسين محمد المشهداني --- Saheb J. Abdoul-Rahman صاحب جمعة عبدارحمن

Tikrit Journal for Agricultural Sciences مجلة تكريت للعلوم الزراعية
ISSN: 18131646 Year: 2014 Volume: 14 Issue: 1 Pages: 270-278
Publisher: Tikrit University جامعة تكريت

Abstract

The study aimed to investigate some effects of the zinc and selenium on some blood picture (Hb, Pcv and WBCs) and the concentrations of Testosterone hormone (testo.), Luteinizing Hormone (LH), Prolactin (PRL) in the male rates testo exposed to oxidative stress induced by hydrogen peroxide. The study included (40) male albino rats,(3-4) months ages and (245-280) gm weight were divided to (8) groups both group with (5) rats as follows:Control group, hydrogen peroxide (H2O2) 1% group, zinc(100 mg Zn/Kg of food)+ H2O2 (1%) group,selenium(100 μg Se/Kg of food)+ H2O21% group, zinc (100mg) and selenium(100 g)+ H2O2(1%)group, zinc group(100 mg Zn/Kg of food), selenium group(100 μg Se/Kg of food) and zinc(100mg) and selenium(100 μg) together group.The results showed a significant decrease(p≤ 4.45) in the concentration of (testo), (LH) and the values of Hb , PCV in the group exposed to oxidative stress induced by hydrogen peroxide compared with the control group. The WBCs showed significant increase in the group exposed to oxidative stress induced by hydrogen peroxide compared with the control group While non significant differences showed in the concentration of prolactin hormone in the study group.The groups exposed to oxidative stress and treatment with zinc, selenium and zinc,selenium together showed significant increase in the in concentration of testo, LH, Hb, and PCV, significant decrease in WBCs when compared with a hydrogen peroxide group.The group treatment zinc and selenium shwed significant increase in value Hb, While non significant differences showed in the concentration of Tsto, LH, PCV and WBCs when compared with control group.The treatment of animals by zinc and selenium together showed significant increase in the in concentration of Testototo, LH and Hb, While non showed significant differences in the values of PCV, WBCs when compared with control group.

Keywords

Antioxidant --- albino --- stress --- جرذان بيض ، اجهاد تأكسدي ، زنك ، سيلينيوم