Synthesis of New 1,3-Oxazole Derivatives

Abstract

1,3- Oxazole derivatives (2a – d) have been Synthesized by cyclization of hippuric acid with different aromatic aldehydes , hippuric acid was readily obtained by reaction of benzoyl chloride with glycine (2-amino acetic acid) . Compounds (2a – d) were converted in to aviary of derivatives. All new compounds were characterized by 1H NMR, FTIR and UV spectroscopy