The Effects of Zinc Phosphide and Brodifacoum on Mitotic Index and Chromosomal Aberrations in Germ Cells of Wild type and Laboratory Mice (Mus Musculus)

Abstract

The genotoxic effects of two wildy used rodenticides in Iraq (Zinc phosphide and Brodifacoum) were studied in wildtype and Balbc mice,by using mitotic index(MI) and chromosomal aberration (CA). The results showed that both rodenticides inhibited the mitotic index of germs cells in both types of mice, but wildtype mice were more sensitive then Balbc mice.In addition both rodenticides were able increase the frequency of chromosomal aberrations.