Synthesis, Characterization, and Biological Study of Some Transition Metal Complexes with Guaifenesin

Abstract

The present work includes the preparation confirmation and bioassay of novel complexes of the ligand [3-(o-methoxy phenoxy-1, 2-propanediol], with metalCr (III), Co (II), Ni (II) and Cu (II) were also formed and studied. The new complexes were characterized by FT-IR Spectroscopy and UV-Visible spectroscopy.The metal complexes have been tested in vitro against a number of microorganisms (gram positive bacteria (Staphylococcus aureus) and gram negative bacteria (Pseudomonas aeruginosa)) in order to assess their antimicrobial properties. All our complexes showed considerable activity against all bacteria.