A Study of Hepatotoxic ofGlucophage in Holy Karbala Province
KARBALĀʾ HERITAGE Quarterly Authorized Journal Specialized in Karbalāʾ Heritage
2015, Volume 2, Issue ع2 -ج2, Pages 284-298
2015, Volume 2, Issue ع2 -ج2, Pages 284-298
Abstract
AbstractThe present study aimed at detecting the side effect ofGlucophage on with diabetes with its both types , first and thesecond by applying it on the five tissue of white albino mice. Three doses were taken in this study of 50 100 and 150mg Kg for four weeks period . The results obtained showedthat the dose 150 mg had caused changes in the liver of themice , infiltration and congestion presence of edema fluidand changes in the cytoplasm of hepatocyte also occurred inthe liver of mice . The study came out with the result thatthe Glucophage drug should be taken in low doses that thepatients with diabetes . The study was carried out in thelaboratories of Karbala University .
Keywords
Abstract The present study aimed at detecting the side effect of Glucophage on with diabetes with its both types, first and the second by applying it on the five tissue of white albino mice . Three doses were taken in this study of 50 100 and 150 mg Kg for four weeks period . The results obtained showed that the dose 150 mg had caused changes in the liver of the mice, infiltration and congestion presence of edema fluid and changes in the cytoplasm of hepatocyte also occurred in the liver of mice . The study came out with the result that the Glucophage drug should be taken in low doses that the patients with diabetes . The study was carried out in the laboratories of Karbala University .Metrics