A Study of Hepatotoxic ofGlucophage in Holy Karbala Province

Abstract

AbstractThe present study aimed at detecting the side effect ofGlucophage on with diabetes with its both types , first and thesecond by applying it on the five tissue of white albino mice. Three doses were taken in this study of 50 100 and 150mg Kg for four weeks period . The results obtained showedthat the dose 150 mg had caused changes in the liver of themice , infiltration and congestion presence of edema fluidand changes in the cytoplasm of hepatocyte also occurred inthe liver of mice . The study came out with the result thatthe Glucophage drug should be taken in low doses that thepatients with diabetes . The study was carried out in thelaboratories of Karbala University .