Pathological Effects of Endosulfan Pesticide on Common Carp Cyprinus carpio

Abstract

The present study done at the college of Veterinary Medicine University of Baghdad. The chronic toxic effects of endosulfan was investigated with conferments on histopathological effect of infected organ in Cyprinus carpio. Different concentrations of endosulfan 0.0001 µg/L, 0.0002µg/L, 0.0003µg/L, 0.0004µg/L and 0.0005µg/L were used to study the chronic effects of endosulfan exposure to 60 fingerlings for 90 days in fish organs mainly gills, liver, kidney, muscles and brain.Histopathological changes in gills characterized by lamellar fusion, extensive odema of primary lamellar epithelium, telengiectasis of secondary lamellar as well as severe destructive changes of epithelial lamellae while or diffuse necrosis, congestion with marked mononuclear cells infiltrate mainly surrounding bile duct. Kidneys results varying degrees of tubular necrosis with severe congestion and hemosiderosis together with melanomacrophage infiltration. Muscular tissues showed fragmentation and separation of muscle bundles with intramuscular odema with necrotic changes accompanied with distortion of surviving structure. Severe vascular changes were seen in all organs including brain with severe vacuolar changes (spongiosis) of neurons