ROLE OF STAPHYLOCOCCUS SAPROPHYTICUS PEPTIDOGLYCAN IN LIVER AND KIDNEY DYSFUNCTIONS

Abstract

The effect of peptidoglycan extracted from Staphylococcus saprophyticus on liver and kidney functions was studied in rabbits, by means of injecting a group of Albino white rabbits intravenously with 6 mg / ml of partially purified S. saprophyticus S67 peptidoglycan extract. The levels of urea, creatinine, glucose, GOT, GPT, alkaline phosphatase were estimated. The results showed a significant increase (P≤0.05) in those parameters in exception of alkaline phosphatase since it developed a significant (P≤0.05) decrease, however such results may indicate that the peptidoglycan caused dysfunction in both of liver and kidney.