Drug-food Interaction of Ceftriaxone Used in Treatment of Different Diseases with Food containing - Calcium Products for In-patients of the Didactic Parturition Hospital of Al-Zahraa’

Abstract

The study was carried on 402 clinical cases of in-patients pediatric patients of the Dedacticparturition Hospital of Al-Zahraa’. They were treated with different medications [(244 clinical cases of male in-patients and 158 clinical cases of female in-patients, table 1) against different diseases infection, table 1 (Meningitis, Pneumonia, Enteritis and Bronchitis)]. The data partook of the drug-food interaction between a drug (Ceftriaxone) with calcium containing - food (milk, which are including artificial and normal lactation) (table 1) (figure 1). The results showed that the four factors (normal lactation, artificial lactation, treatment by Ceftriaxone and non treatment by Ceftriaxone groups) had the same average effect on the gender (male and female) of peadiatric in-patients of the Dedactic Parturition Hospital of al-Zahraa’. Superiority was of (treated by Ceftriaxone) group according to (non treated by Ceftriaxone)] group on each the gender (male and female) (p<0.05), In other hand there were no significant differences (p<0.05) between (normal and artificial lactation) on the in-patients (male and female) and both of them had the same average effect on the in-patients peadiatric in the Dedicated Hospital of Al-Zahraa’. These results were calculated by two way analysis (ANOVA and F-test analyze).Objectives Studying the drug - food interactions between the antibiotic (Ceftriaxone) that it is used in treatment of different diseases and calcium containing-products (milk), and their effect of both of them on the gender (male and female) that they have artificial and normal lactation for in-patients of Dedactic Parturition Hospital of al-Zahraa’. Materials and Methods The data were taken randomly from the peadiatric in-patients' files of the Statistics Department of the Didactic Parturition Hospital of al-Zahraa’. These data included 402 clinical cases of in-patients [(244 clinical cases of male pediatric in-patients and 158 clinical cases of female pediatric in-patients, table1). They were treated with different medications against different diseases (four disease states)]. These data were analyzed statically with SPSS 8.0 statistical package (ANOVA- analysis of variance - two way analysis), also the values between groups were compared by independent sample (F- test). (P) values less than or equal to 0.05 has been evaluated as statistical significant [Wayne, 2010].Conclusions Ceftriaxone and non treatment by Ceftriaxone groups of pediatric in-patients have the same average effect on the gender (male and female) of peadiatric in-patients of the Didactic Parturition Hospital of al-Zahraa’ .Superiorities of groups of the pediatric in-patients that treated with antibiotic (Ceftiaxone) according to the another groups on the gender (male and female).