Determinatin of Aldose Reductase (AR) activity in Diabetic Patients

Abstract

The current study included estimation of Aldose reductase (AR) activity in serum of diabetic patients. The study included (47) samples of seram from diabetic patients serum (both types I and II), the patients age ranged from (9-80) years old, and (36) samples of seram from healthy people (control group) aged between (12-80) years old. The results showed significant elevation (P <0.05) in the AR activity in diabetic patients for both types compared with control group. The AR activity was (38.65 ±9.60) IU/ L in the serum of type II diabetes patients and (29.52 ± 5.75) IU/ L in patients with type I diabetes, compared to (11.01 ± 2.19) IU/ L in the serum of healthy people.