The study of Oxidative stress, Sperm chromatin abnormality and seminal parameters in different groups for infertile patients


The study was carried out between January 2014 and October 2014 including one hundred and fifty five infertile men who attended the Fertility center in AL-Sadr Medical City. The Objective of this study was to study of oxidative stress, sperm chromatin abnormality and semen quality including ( semen volume, Liquefaction time, sperm concentration, motility, and normal morphology. The results of the study showed that there was a significant increase (p<0.05) in the semen volume, sperm concentration, progressive motility and normal morphology for unexplained compared to five abnormal semen groups. Also it was a significantly decrease (p<0.05) in liquefaction time, leukocyte concentration, MDA concentration and sperm chromatin abnormality for unexplained compared with abnormal semen groups. This study supports the conclusion that oxidative stress in seminal plasma is the main causes of sperm chromatin defect with defect of semen parameters and related with male infertility.