The Systemic Host Modulation Therapy of Periodontal Diseases

Abstract

Background: The systemic host modulation therapy is new approach in treatment of periodontal diseases.Materials and methods:The target of this treatment is the host response to microbial infection because at presenttime,it is well known that most of damage found in periodontal diseases cause by the inflammatory -immuneresponse to periodontal infections.Sub-antimicrobial-dose Doxycycline (SDD) is a 20-mg dose of Doxycycline(Periostat) that is approved and indicated as an adjunct to scaling and root planning (SRP) in the treatment ofchronic periodontitis.Results:At present, SDD (Periostat) is the only systemically administered agent that is approved by the U.S. Food andDrug Administration (FDA) and accepted by the American Dental Association (ADA

Keywords

Periostat.