A preliminary Evaluation of the Effect of Pure Protein Extract Obtained from Loligo sp. (Mollusca: Cephalopoda) on Cancer cell line (Hela) and on Normal Cell Line (REF)

Abstract

In this study the capacity of pure Loligo sp. extract was studied on two celllines Hela cell line and normal line of rat embryo fibroblast (REF) in vitro. The extract ofLoligo sp. showed a high inhibition activity on Hela cell line in all concentrations usedand the highest effect was appeared after 48 hours of exposure with a concentration1000μg/ml inhibition; result of this cell were 42.79% for extract and bio result of thesecells explained inhibition for biology of cell depended on concentration of pure extract,while it was low effect on REF exposure time 48 hrs.