Antimicrobial activity of chitosan isolated from fungus Rhizopus oryzae

Abstract

In this study chitosan was isolated from the fungus Rhizopusorayzae by using yeast peptone glucose broth medium (YPG) at the late stationary phase. Chitosan production from mycelium reached to 15 mg/g as dry weight . 25% was the N-acetylation of chitosan while 96% for the D-glucosamine. Chitosan showed antimicrobial activity against Escherichia coli, Staphylococcus aureus and Candida albicans and reach to 20 , 15 and n 15 mm as inhibition zone respectively