STUDY OF ANAESTHETIC, PHYSIOLOGICAL AND BIOCHEMICAL EFFECTS OF KETAMINE COMBINATION WITH FENTANYL AND DIAZEPAM IN RABBITS

Abstract

The study was conducted at the animal house of the collage of Veterinary medicine university of Basrah, the objective of this study to know effect ketamine drug as anesthetic agent in rabbits and comparison between several types of general anesthetic systems in rabbits and study the combination with Diazepam and fentanyl , in this study used (32) adult domestic rabbits from both gender , the average of body weight (1000-1900) grams , the rout of administration by intramuscular , were divided equally and randomly into four groups (8) rabbit in each groups .We were studied the induction time, surgical anesthesia time and recovery time also we were studied some physiological parameter (heart rate, respiratory rate and body temperature), also we were recorded (Degree of Analgesia, Eyes Reflexes and Degree of Muscle Relaxation).We were recorded data of this parameter before I.M administration at (Zero) minute and after I.M administration depending the following time (5, 10, 20, 30, 40, 50, 60) minute, until response the rabbit to external stimuli.The biochemical test are (ASTand ALT).

Keywords

Ketamine, Rabbits, ALT.