The effect of aluminum chloride and acetic acid in some blood picture of male rats

Abstract

The current study was conducted to investigate the poisonous effects of Aluminum Chlorid dissolved in water alone and its effects of dissolved in acetic acid 25% in blood variables for male rats of Mus musculus . fifteen rats of the species Mus musculus ages (3-4) weeks and weights of (100±150gm) were used in this study. The study included tow experiments, (25) rat used for each experiment, which included (5) groups with (5) rat each. The first group of each experiment groups was considered the control group ,while the remaining four groups were considered as treatment groups. The first group were treated with (70 mg/kg of bodyweight) of Aluminum Chloride for different intervals (2, 5, 10, and 20 days); the second group given (70 mg/kg bodyweight) of Aluminum Chloride dissolved in acetic acid 25%. the blood variables for all rats were calculated after the different injection intervals was finished and dissected and blood was taken directly from the heart and put in experimental tube containing anticoagulant EDTA , The results showed low corporate rate of red blood cells ( RBC) and other blood variables and high moral in the rate of white blood cells ( WBC) compared to the control group, these changes were gradual as the dosage period.