Effect of Electromagnetic Radiations in Some Biochemical Parameters and Histopathological Changes for Laboratory Male Rats Rattus norvegicus

Abstract

The present study was designed to investigated the effect of electromagnetic radiations emitted from mobile phone devices in some biochemical parameters and histopathological changes of kidney and liver for male laboratory rats Rattus norvegicus . Forty eight of male rats were divided randomly into eight groups and each group consist of six rats . Four groups of these were exposure to electromagnetic radiations by mobile phone that put in cages at different time periods included (1, 2, 3 and 6 month) while the other residual groups were considered as a control groups at same time periods . After ending up time periods of exposure , every animals were dissect and collected of blood samples for the purpose of biochemical parameters measurement . As such kidney and liver have eradication, which kept in proven solution (formalin 10%) to paving preparing tissues sections . Electromagnetic radiations caused an increasing in concentration of urea and creatinine for exposure animals groups when comparing with control groups . The results revealed a significant decrease ( P≤0.05) in liver enzymes which comprises ALT , AST and ALP in all exposure groups when comparing with control groups except (exposure2) group in ALP that did not observe significant difference compared to (control 2) group . The gradual decrease was observed in ALT , AST and ALP when comparing between all exposure groups . The results were indicated increase in level of cholesterol and triglyceride for all exposure groups compared to control groups , the increase was elevated between all exposure groups by progressive time exposure to electromagnetic radiations . In the other hand the kidney showed histopathological changes included congestion of vessels , haemorrhage was happened between renal tubules accompanied by inflammatory cells infiltration with breaking down of renal glomeruli while the contraction, absence of glomeruli and enlargement of space Bowman ,s capsule were observed in another tissue sections , the renal tubules was affected by electromagnetic radiations which breakage the walls of renal tubules and it loss the natural structure .The electromagnetic radiations exposure led to histopathological changes in livers of animal included congestion of the central vein , congestion of sinusoids with heavy infiltration of inflammatory cells , besides pathological changes were varied to involve haemorrhage of livers , vacuolation of hepatocytes as well as appearance edema statuses .