The Effect of Methanolic Extract of Quercus infectoria Against Some Causative Agents of Diarrhea and Eliminate their Antimicrobial Resistance

Abstract

We obtained 124 bacterial isolates including: Escherechia. coli. I (35 isolates 7%) isolates, E. coli II (8 isolates 1.6%), E. coli III (17 isolates 3.4%), E. coli IV (22 isolates 4.4%), Shigella dysenteriae (8 isolates 1.6%), Salmonella arizonae (16 isolates 3.2%), Salmonella typhi (12 isolates 2.4%) and Vibrio cholera (6 isolates 1.2%) Sensitivity test showed high resistance to amoxicillin/clavulanic acid, amoxicillin, ampicillin, erythromycin, streptomycin, nitrofurantoin, cefixime, rifampicin, tetracycline, trimethoprim - sulfamethoxazole and tobramycin. Most of the isolates appeared sensitive to nalidixic acid, gentamycin, amikacin, doxycyclin, cefotaxime, cephalexine and chloramphenicol. All isolates were sensitive to ciprofloxacin. The MIC of the methanol extracts of Quercus infectoria against different pathogenic bacteria was ranging between 2.5 mg/ml - 20.0 mg / ml and the MBC was 1.25 mg/ml - 20.0mg/ ml. The isolates revealed high resistance to most widely used antibiotic, the methanol extracts of Quercus infectoria showed high potential as antibacterial agent.