Histopathologic Study for Skin Basal Cell Carcinoma

Abstract

background: Basal cell carcinoma (BCC) is the most common Worldwide cutaneous cancer; approximately 75% of all skin cancers. It arises from the basal cells of the epidermis and pilosebaceous units. It has a long evolution, slow growth rate with up to 70% of primary BCCs occurring in head or neck region. Although it rarely results in death or metastatic disease, BCC can cause significant morbidity due to destructive local spread.Aims of the study: To determine the frequency of various histopathologic types of BCCs encountered in practice, to delineate the spectrum in setup, anatomical location, site predilection, and annual age and sex incidence each year.Materials and Methods: The analysis included two hundreds and five cases of skin tumors, 88 cases were basal cell carcinoma from Department of Histopathology, Al Hussain Medical City/ Karbala. The study was retrospective and done during the period of January 2012 to June 2016. After careful review of the Hematoxylin and Eosin (H and E) stained sections, statistical analyses were done.Results: Out of (205 cases of skin tumors) only 88 were of BCC and accounted for 42.92% of all the malignant tumors of skin. majority (87.51.%) of the lesions of BCC were located on head and neck region, solid nodular type was most common histopathologic type and average age of cases was 64 5years. Conclusion: In the present study majority (87.51.%) of the lesions of BCC were located on head and neck region, average age of cases of basal cell carcinoma was 64.5years, and solid nodular type of BCC was most common type.