Synthesis ,Characterization and Identification of New Oxazepine,Oxazepane and Oxazinane Compounds from reaction of ٍ Some )Z)-2-((2-hydroxybenzylideneamino)methyl)-2-(hydroxymethyl)propane-1,3-diol Derivatives with some cycloanhydrides.

Abstract

:- Z)-2- ((2-hydroxybenzylideneamino)methyl -2 -(hydroxy)propane -1,3-diol,)E) -4- (3-hydroxy-2,2-bis (hydroxyl methyl) propylimino)pentan-2-one, -2- ((4-(hydrazonopentane -2-ylideneamino methyl)-2 -(hydroxyl methyl)propane-1,3-diol and (Z)-2-((4-amino-1,5-dimethyl-2-phenyl-1H –pyrazol-3(2H)-ylideneamino)methyl)-2-(hydroxymethyl)propane-1,3-diol were prepared by condensation of 2-(aminomethyl)-2-(hydroxymethyl)propane-1,3-diol with 2-hydroxy benzaldehyde, pentane-2,4-dione, (E)-4-hydrazonopentan-2-one and 4-amino-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one .These Schiff- bases were reacted with Succinic, Maleic and Malonic anhydride in absolute ethanol to give 6,7-membered heterocyclic ring system Oxazepine,Oxazepane,Oxazinan.The Schiff-bases and the final products were identified by their melting points, elemental analysis, FT-IR and UV-Visible spectra.