A STUDY OF THE EFFECT OF COMBINATION OF CEFTAZIDIME AND EDTA ON SOME TYPE OF BACTERIA ISOLATED FROM INFECTED WOUND.

Abstract

:A total of 100 swab samples were obtained from patients suffering from woundinfection. The isolates were identified using different microscopical cultural characteristics andbiochemical tests. Final identification of gram negative bacteria were performed by using API 20 Esystem. The most common bacteria isolates was Pseudomonas aeruginosa (37.64 %) followed byStaphylococcus aureus (23.52%). Escherichia coli and Klebsiella spp. (14.11%) each of them.Followed by Proteus mirabilis (8.23%), finally Enterococcus faecalis and Serratia marcesence(1.17%) each of them.Sensitivity of the isolates to antibiotic leveled high resistance to Amoxicillin,cefotaxime, ceftazidime, Gentamicin and Tobramycin. To less extent was the resistance toCiprofloxacin, Amikacin, Cefepime, imipenem, norfloxacin, P-ofloxacin and Azitromycin.Combination of EDTA and ceftazidime gave interesting results against the local bacterial isolates.Itwas concluded from this study the possibility of using a combination of Ceftazidime with EDTA totreat infected wounds with high success rate