Pathogenic effect of Entamoeba gingivalis on gingival tissues of rats

Abstract

Entamoeba gingivalis was isolated from patients suffering of periodontal problem cultured on a special culture, a suspension of the parasite made and spreaded on the gingival margins of three groups of rats: The first group gives immunosuppressive drugs (prednisolone acetate), while not given to the other two groups. Results show the rat’s gingival tissues of the 1st group became red and swollen within 2 days while a mild inflammation occurs at the gingival tissue of the 2nd group and no lesion or inflammatory process occurs to the third group (control). This experiment revealed that Entamoeba gingivalis may become pathogenic in immunocompromised indi-viduals.