The Effect of Intra‑abdominal Carbon Dioxide Pressure on Blood Pressure in Laparoscopic Surgeries

Abstract

Backgrounds: The high intra‑abdominal carbon dioxide (CO2) gas pressure of the pneumoperitoneum may result in physiological changes.Objectives: This study aimed to examine the impact of high CO2 pressure on intraoperative blood pressures (BPs) in patients undergoinglaparoscopy surgeries. Materials and Methods: In this quasi‑experimental clinical trial, 36 patients diagnosed with different intra‑abdominaldiseases were undergone laparoscopic surgeries under a standard of CO2 pressure (≥13 mmHg). In another group, 39 patients who were matchedin age and gender were undergone laparoscopic surgeries under low CO2 pressure (≤12 mmHg). Results: The patients in both high and lowCO2 pressure groups were comparable in age (37.65 vs. 42.37 years; P = 0.114), gender (P = 0.212), and operation time (36.18 vs. 34.64 min),respectively. The patients underwent high CO2 pressure had significantly lower levels of diastolic BP after anesthesia (72.28 vs. 77.89; P = 0.020),lowest systolic BP (SBP) (94.69 vs. 102.26; P = 0.006), and lowest diastolic BP (DBP) (59.00 vs. 68.36; P < 0.001) in contrast with higherlevel of postoperative diastolic BP in high CO2 group (111.23 vs. 78.11; P < 0.001). SBP and DBP and heart rate were decreased significantlyfrom preoperative to postanesthesia and postoperative surgery in groups. Conclusion: The present study showed that BP parameters weredeceased following laparoscopy surgeries (higher pneumoperitonial CO2 pressure has lower BP in comparison to lower pneumoperitonial CO2pressure). Low CO2 pressure is recommended during laparoscopic surgeries as much as possible, especially in patients with comorbiditiessuch as heart diseases, old ages, and for operations that take longer time.