EFFECT OF SUB INHIBITORY CONCENTRATIONS OF ANTIBIOTICS ON ADHERANCE OF PSEUDOMONAS AERUGINOSA

Abstract

ABSTRACTSusceptibility of various isolates of P. aeruginosa to various antibiotics wastested. Ciprofloxacin was found to be the most effective antibiotic. Minimuminhibitory concentrations for ciprofloxacin, Gentamicin, piperacillin andcefotaxime, were specified and ciprofloxacin was found having the lowest MICas compared with others . The effect of sub MIC ( ¾ , ½ , ⅓ and ¼ ) of thesefour antibiotics on adhesion capability of the isolates was tested. Cefotaxime wasuneffective as comparied to gentamycin, ciprofloxacin and piperacillin. ¾ MICof ciprofloxacin was found the most effective concentration for attenuation ofadherence capability.__________________________________________________________