Gossypol Effect in Some blood parameters, enzymes and pathology of male common carp Cyprinus carpio l.

Abstract

Gossypol is a substance found in the cottonseed. Recently in Iraq and in other countries the cottonseed was used as a concentrate for fish and other animals without awareness of the risk. The present study is designed to shed the light on the deleterious effect of gossypol on some hematological parameters and enzymes of male common carp Cyprinus carpio l.. Oral administration of gossypol 20 mg./kg. b.w. for ten days was found to be a strong lyses for red blood cell, reduced packed cell volume and increased erythrocyte sedimentation rate and decreased total white blood cell. Furthermore alkaline phosphotase, alinine aminotransferase and aspartate aminotransferase were increased which reflect liver and kidneys damage caused by gossypol coincided with the histopathological changes in which there was mainly degeneration as well as inflammatory cells infiltration.